Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4230982 | 0.94 | HCAR3 (0.41) | DTYMKHCAR3CA1CA2TPMT | |
| SCHEMBL7226064 | 0.87 | PDE4D (0.38) | DTYMK | |
| SCHEMBL6989382 | 0.87 | PDE4D (0.38) | DTYMK | |
| SCHEMBL31151988 | 0.85 | PDE5A (0.43) | PDE5AALDH1A1 | |
| SCHEMBL31145791 | 0.85 | PDE5A (0.43) | PDE5AALDH1A1 | |
| SCHEMBL31510002 | 0.84 | DTYMK (0.39) | DTYMKHCAR3PKMCASP6PDE5A | |
| SCHEMBL1446568 | 0.82 | GPR119 (0.46) | ALDH1A1 | |
| SCHEMBL5228256 | 0.80 | DTYMK (0.38) | DTYMKCA1CA2TPMTPKM | |
| SCHEMBL38658208 | 0.79 | NPC1 (0.40) | PDE5ASNCATSHRMEN1ALDH1A1 | |
| SCHEMBL16945800 | 0.79 | PKM (0.55) | DTYMKTPMTPKMTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024193691-A1 | CONJUGATE OF ANTI-ROR1 ANTIBODY AND PBD COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏恒瑞医药股份有限公司 | 2024-09-26 | — | — | WO | disclosed |