Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 7/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31146023 | 0.86 | PDE2A (0.34) | MAPK1PDE2AGPR139BRD4PPARG | |
| SCHEMBL31145880 | 0.82 | MAPK1 (0.38) | MAPK1PDE2AGPR139BRD4PPARG | |
| SCHEMBL31146176 | 0.82 | MAPK1 (0.38) | MAPK1PDE2AGPR139BRD4PPARG | |
| SCHEMBL31146016 | 0.82 | MAPK1 (0.38) | MAPK1PDE2AGPR139BRD4PPARG | |
| SCHEMBL31145831 | 0.80 | PDE2A (0.38) | MAPK1PDE2AGPR139PPARGIDH1 | |
| SCHEMBL31145972 | 0.80 | PDE2A (0.36) | MAPK1PDE2AGPR139IDH1 | |
| SCHEMBL31161025 | 0.78 | MAPK1 (0.37) | MAPK1PDE2AGPR139AURKAAURKB | |
| SCHEMBL31146394 | 0.75 | PDE2A (0.38) | MAPK1PDE2AGPR139AURKAAURKB | |
| SCHEMBL31145813 | 0.74 | GPR139 (0.40) | MAPK1PDE2AGPR139 | |
| SCHEMBL31146112 | 0.73 | GPR139 (0.40) | MAPK1PDE2AGPR139IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688748-A1 | QUINOLINONE AMIDE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024206339-A1 | QUINOLINONE AMIDE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2024-10-03 | — | — | WO | disclosed |