Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2707356 | 0.83 | LMNA (0.45) | LMNAMAPTALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL31146874 | 0.80 | LMNA (0.42) | LMNAMAPTALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL6094086 | 0.80 | LMNA (0.47) | LMNAALDH1A1CYP2D6CYP1A2TSHR | |
| SCHEMBL30742985 | 0.78 | LMNA (0.48) | LMNAMAPTALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL21544332 | 0.77 | ALDH1A1 (0.52) | LMNAMAPTALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL29471046 | 0.77 | KDM4E (0.41) | LMNAMAPTALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL29471044 | 0.76 | LMNA (0.39) | LMNAMAPTALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL29809031 | 0.75 | ALDH1A1 (0.46) | LMNAMAPTALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL20516746 | 0.75 | LMNA (0.48) | LMNAMAPTALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL30600902 | 0.75 | LMNA (0.48) | LMNAMAPTALDH1A1CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680606-A1 | ADENINE DERIVATIVES AS HSP90 INHIBITORS | AtmosR (FR) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024194175-A1 | ADENINE DERIVATIVES AS HSP90 INHIBITORS | ATMOSR (FR) | 2024-09-26 | — | — | WO | disclosed |