Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2707665 | 0.83 | NPC1 (0.41) | LMNAMAPTNPC1RAB9AAPLNR | |
| SCHEMBL6096777 | 0.83 | LMNA (0.51) | LMNAMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL4766444 | 0.81 | DCTPP1 (0.43) | MAPTNPC1RAB9ANPY1RAPLNR | |
| SCHEMBL31146891 | 0.80 | LMNA (0.49) | LMNAMAPTNPC1RAB9AAPLNR | |
| SCHEMBL25381487 | 0.78 | LMNA (0.47) | LMNAMAPTNPC1RAB9AAPLNR | |
| SCHEMBL29471047 | 0.77 | KMT2A (0.44) | LMNAMAPTNPC1RAB9AKMT2A | |
| SCHEMBL1457286 | 0.77 | NPC1 (0.45) | MAPTNPC1RAB9AAPLNRKMT2A | |
| SCHEMBL29471043 | 0.77 | NPC1 (0.36) | LMNAMAPTNPC1RAB9AAPLNR | |
| SCHEMBL31600773 | 0.76 | LMNA (0.42) | LMNAMAPTNPC1RAB9AAPLNR | |
| SCHEMBL8793065 | 0.74 | PDE3B (0.46) | LMNAMAPTNPC1RAB9ANPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680606-A1 | ADENINE DERIVATIVES AS HSP90 INHIBITORS | AtmosR (FR) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024194175-A1 | ADENINE DERIVATIVES AS HSP90 INHIBITORS | ATMOSR (FR) | 2024-09-26 | — | — | WO | disclosed |