Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KHK | P50053 | 1/20 | 0.49 |
| ▸ | ULK1 | O75385 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 3/20 | 0.48 |
| ▸ | JAK1 | P23458 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12286618 | 0.80 | JAK2 (0.63) | SMN1; SMN2KMT2APOLBMEN1ULK1 | |
| SCHEMBL22445917 | 0.80 | ULK1 (0.48) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL8769868 | 0.79 | SMN1; SMN2 (0.64) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL22445828 | 0.77 | RAB9A (0.51) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL1973642 | 0.77 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL3147407 | 0.76 | POLB (0.60) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL21254596 | 0.76 | SMN1; SMN2 (0.57) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL18167981 | 0.76 | JAK2 (0.52) | ULK1JAK2JAK1LRRK2 | |
| SCHEMBL1666122 | 0.75 | RAB9A (0.80) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL22445881 | 0.75 | LRRK2 (0.58) | NPC1RAB9ASMN1; SMN2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118984827-A | GLP-1R modulating compounds | 歌礼生物科技（杭州）有限公司 | 2024-11-19 | — | — | CN | disclosed |