Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.41 |
| ▸ | CASP1 | P29466 | 7/20 | 0.41 |
| ▸ | CASP7 | P55210 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28081996 | 0.82 | KDM4E (0.43) | ALDH1A1CYP1A2HPGDHSD17B10CASP1 | |
| SCHEMBL5800464 | 0.79 | LCK (0.45) | ALDH1A1CYP1A2HPGDHSD17B10CASP1 | |
| SCHEMBL25216474 | 0.79 | PTPN11 (0.56) | MAPTALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL30422622 | 0.79 | PTPN11 (0.56) | MAPTALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL16671809 | 0.78 | MEN1 (0.52) | ALDH1A1CYP1A2HPGDHSD17B10CASP1 | |
| SCHEMBL6883115 | 0.77 | SCN9A (0.47) | ALDH1A1CYP1A2HPGDHSD17B10CASP1 | |
| SCHEMBL9684571 | 0.77 | ADORA3 (0.49) | MAPTALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL25212173 | 0.76 | HDAC6 (0.43) | MAPTCASP1LMNAPTPN11KMT2A | |
| SCHEMBL31485454 | 0.76 | HDAC6 (0.43) | MAPTCASP1LMNAPTPN11KMT2A | |
| SCHEMBL30422885 | 0.76 | HDAC6 (0.43) | MAPTCASP1LMNAPTPN11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118748995-A | 5-Pyrimidine carboxamide derivatives and methods of use thereof | 亚根达医疗公司 | 2024-10-08 | — | — | CN | disclosed |