⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28870275 | 0.80 | — | — | |
| SCHEMBL5375204 | 0.80 | — | — | |
| SCHEMBL3115140 | 0.80 | — | — | |
| SCHEMBL5370389 | 0.76 | CYP1A2 (0.36) | — | |
| SCHEMBL6656641 | 0.76 | GABRA1 (0.46) | — | |
| SCHEMBL16797132 | 0.74 | TYK2 (0.41) | — | |
| SCHEMBL16797148 | 0.74 | CYP1A2 (0.42) | — | |
| SCHEMBL5394326 | 0.74 | CA12 (0.46) | — | |
| SCHEMBL329345 | 0.71 | — | — | |
| SCHEMBL23239 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429308-B | Synthesis process of diclofenac sodium | 安徽普利药业有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-114409611-A | Oxadiazole hydrazide compound and preparation method and application thereof | 贵州大学 | 2022-04-29 | — | — | CN | claimed |
| CN-113429308-A | Process for synthesizing diclofenac sodium | 安徽普利药业有限公司 | 2021-09-24 | — | — | CN | claimed |
| EP-3080090-B1 | BICYCLIC HETEROARYL INDOLE ANALOGUES USEFUL AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS SA (CH) | 2018-01-31 | — | — | EP | claimed |
| US-9682977-B2 | Bicyclic heteroaryl indole analogues useful as ROR gamma modulators | GLENMARK PHARMACEUTICALS S.A. (CH) | 2017-06-20 | — | — | US | claimed |
| US-20160326163-A1 | BICYCLIC HETEROARYL INDOLE ANALOGUES USEFUL AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2016-11-10 | — | — | US | claimed |
| EP-3080090-A1 | BICYCLIC HETEROARYL INDOLE ANALOGUES USEFUL AS ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2016-10-19 | — | — | EP | claimed |
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |
| WO-2015087234-A1 | BICYCLIC HETEROARYL INDOLE ANALOGUES USEFUL AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-06-18 | — | — | WO | claimed |
| US-8937078-B2 | Quinazolinones as prolyl hydroxylase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2015-01-20 | — | — | US | claimed |
| US-6150360-A | ADMINISTERING TO A PATIENT SUFFERING FROM HUMAN IMMUNODEFICIENCY VIRUS INFECTION A TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVE | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-11-21 | — | — | US | claimed |
| WO-1999050256-A1 | TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-10-07 | — | — | WO | claimed |
| US-5344834-A | Functionalized vinyl azoles and methods of use | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-09-06 | — | — | US | claimed |
| EP-0380712-A1 | Process for the preparation of 2,6-dichlorodiphenylaminoacetic-acid derivatives | HEUMANN PHARMA GMBH & CO (DE) | 1990-08-08 | — | — | EP | claimed |
| EP-0011928-B1 | 3,5-DIHYDROXYPENTANOIC ESTER DERIVATIVES HAVING ANTIHYPERLIPAEMIC ACTIVITY, THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1982-04-28 | — | — | EP | claimed |
| US-4255444-A | ANTICHOLESTEROL AGENTS | SANKYO COMPANY LIMITED (JP) | 1981-03-10 | — | — | US | claimed |
| US-4248889-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY LIMITED (JP) | 1981-02-03 | — | — | US | claimed |
| EP-0011928-A1 | 3,5-Dihydroxypentanoic ester derivatives having antihyperlipaemic activity, their manufacture and pharmaceutical compositions containing them | SANKYO COMPANY LIMITED (JP) | 1980-06-11 | — | — | EP | claimed |
| EP-0010951-A1 | 4-Hydroxy-2-pyrone derivatives, process for their preparation and their pharmaceutical preparations | SANKYO COMPANY LIMITED (JP) | 1980-05-14 | — | — | EP | claimed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | claimed |