Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 7/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105571 | 0.86 | LMNA (0.31) | LMNAMAPTHTTL3MBTL1PRNP | |
| SCHEMBL3112202 | 0.84 | NNMT (0.34) | L3MBTL1NPSR1DHODHWDR5 | |
| SCHEMBL3114583 | 0.82 | IRAK4 (0.42) | IRAK4 | |
| SCHEMBL3113328 | 0.80 | LMNA (0.32) | LMNAMAPTHTTL3MBTL1PRNP | |
| SCHEMBL3121431 | 0.78 | CCR8 (0.33) | MAPTADORA2APRNPPPARGNPSR1 | |
| SCHEMBL3108919 | 0.77 | LMNA (0.51) | LMNAATMIRAK4 | |
| SCHEMBL3114988 | 0.77 | LMNA (0.31) | LMNAMAPTHTTL3MBTL1PRNP | |
| SCHEMBL5078617 | 0.72 | DHODH (0.39) | LMNAMAPTDHODHATMIRAK4 | |
| SCHEMBL3117713 | 0.71 | MAPT (0.37) | LMNAMAPTL3MBTL1ADORA2ARXFP1 | |
| SCHEMBL3106873 | 0.71 | MAPT (0.37) | LMNAMAPTADORA2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575064-B2 | Synergistic fungicidal active substance combinations | BAYER CROPSCIENCE AG (DE) | 2013-11-05 | — | — | US | disclosed |
| US-20130281500-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20130281292-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20130281496-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20130274099-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-17 | — | — | US | disclosed |
| US-20130274100-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-17 | — | — | US | disclosed |
| US-20130274101-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-17 | — | — | US | disclosed |
| US-20100273648-A1 | Synergistic Fungicidal Active Substance Combinations | BAYER CROPSCIENCE AG (DE) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281496-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | LMNA 3819/4885MAPT 4293/4885HTT 4294/4885 |
| US-20100273648-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | LMNA 3819/4885MAPT 4293/4885HTT 4294/4885 |
| US-20130281500-A1 | Synergistic Fungicidal Active Substance Combinations | CAT, CYP1A2, GABBR1 | LMNA 3876/4885MAPT 4023/4885HTT 4275/4885 |
| US-20130274100-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | LMNA 3819/4885MAPT 4293/4885HTT 4294/4885 |
| US-20130274099-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | LMNA 3819/4885MAPT 4293/4885HTT 4294/4885 |
| US-20130274101-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | LMNA 3819/4885MAPT 4293/4885HTT 4294/4885 |
| US-20130281292-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | LMNA 3819/4885MAPT 4293/4885HTT 4294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.