Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 6/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20874147 | 0.94 | RAPGEF4 (0.40) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL16913904 | 0.88 | RAPGEF4 (0.36) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL23320398 | 0.87 | RAPGEF4 (0.35) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1900032 | 0.84 | RAPGEF4 (0.44) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL29504768 | 0.84 | RAPGEF4 (0.44) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3199564 | 0.81 | RAPGEF4 (0.38) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL25283314 | 0.80 | F2 (0.37) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL27225358 | 0.79 | RAPGEF4 (0.36) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28628697 | 0.78 | RAPGEF4 (0.35) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28409023 | 0.78 | F2 (0.41) | RAPGEF4F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698544-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024220946-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2024-10-24 | — | — | WO | disclosed |