SCHEMBL31154576

SCHEMBL31154576

Clc1cc2ccccc2o1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
MGLL Q99685 1/20 0.54
HSD17B10 Q99714 1/20 0.54
CYP2A6 P11509 2/20 0.48
FLT3 P36888 1/20 0.48
LOXL2 Q9Y4K0 1/20 0.48
HPGD P15428 2/20 0.47
TYR P14679 1/20 0.47
DAO P14920 1/20 0.47
AKR1B1 P15121 1/20 0.47
POLB P06746 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CDK9 P50750 1/20 0.46
DYRK1A Q13627 1/20 0.46
CA2 P00918 2/20 0.45
MAOB P27338 4/20 0.44
RAB9A P51151 2/20 0.44
MAOA P21397 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL686830 1.00 KDM4E (0.54) KDM4ETDP1MGLLHSD17B10CYP2A6
SCHEMBL6152215 0.79 MAOB (0.43) KDM4ETDP1MGLLHSD17B10CYP2A6
SCHEMBL6152213 0.79 HDAC3 (0.41) KDM4ETDP1MGLLHSD17B10CYP2A6
Ethoxycarbonyl Group SCHEMBL28518665 0.78 CYP2A6 (0.44) KDM4ETDP1MGLLHSD17B10CYP2A6
SCHEMBL103158 0.74 MAOB (0.63) KDM4ETDP1MGLLHSD17B10CYP2A6
SCHEMBL30036439 0.74 MAOB (0.63) KDM4ETDP1MGLLHSD17B10CYP2A6
SCHEMBL3082095 0.73 MAOB (0.63) KDM4EHSD17B10HPGDTYRDAO
SCHEMBL2149843 0.73 MAOB (0.61) KDM4ETDP1HSD17B10HPGDPOLB
SCHEMBL29256707 0.71 KDM4E (0.45) KDM4ETDP1MGLLHSD17B10CYP2A6
SCHEMBL11613110 0.70 MAOB (0.68) KDM4EHPGDSMN1; SMN2CA2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118812500-A Substituted aryl diketone nitrile compound with herbicidal activity, preparation method and application 东北农业大学 2024-10-22 CN disclosed