Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31154576 | 1.00 | KDM4E (0.54) | KDM4ETDP1MGLLHSD17B10CYP2A6 | |
| SCHEMBL6152215 | 0.79 | MAOB (0.43) | KDM4ETDP1MGLLHSD17B10CYP2A6 | |
| SCHEMBL6152213 | 0.79 | HDAC3 (0.41) | KDM4ETDP1MGLLHSD17B10CYP2A6 | |
| Ethoxycarbonyl Group SCHEMBL28518665 | 0.78 | CYP2A6 (0.44) | KDM4ETDP1MGLLHSD17B10CYP2A6 | |
| SCHEMBL103158 | 0.74 | MAOB (0.63) | KDM4ETDP1MGLLHSD17B10CYP2A6 | |
| SCHEMBL30036439 | 0.74 | MAOB (0.63) | KDM4ETDP1MGLLHSD17B10CYP2A6 | |
| SCHEMBL3082095 | 0.73 | MAOB (0.63) | KDM4EHSD17B10HPGDTYRDAO | |
| SCHEMBL2149843 | 0.73 | MAOB (0.61) | KDM4ETDP1HSD17B10HPGDPOLB | |
| SCHEMBL29256707 | 0.71 | KDM4E (0.45) | KDM4ETDP1MGLLHSD17B10CYP2A6 | |
| SCHEMBL11613110 | 0.70 | MAOB (0.68) | KDM4EHPGDSMN1; SMN2CA2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11014596-A | — | — | None | — | — | JP | disclosed |
| CN-111925360-B | 1-heterocyclylisochromanyl compounds and analogs for the treatment of CNS disorders | 赛诺维信制药公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117304196-A | Spiro [ benzofuran-tetrahydropyrrole ] compound, preparation method and application thereof | 三峡大学 | 2023-12-29 | — | — | CN | disclosed |
| CN-110914395-B | Method for preparing hydrogenated fat composition | 邦吉洛德斯克罗科兰有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-116333001-A | Organometallic compound and organic light emitting diode including the same | 乐金显示有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-111171047-B | Fused dihydro-4H-pyrazolo [5,1-C ] [1,4] oxazinyl compounds for the treatment of CNS disorders | 赛诺维信制药公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116283868-A | Synthesis method of spiro [ benzofuran-cyclohexene ] compound | 三峡大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-115121216-B | Water humidifying dechlorinating agent and preparation method and application thereof | 大唐环境产业集团股份有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |
| WO-2022213932-A1 | PYRROLOPYRIMIDINONE COMPOUND AND APPLICATION THEREOF | 广州必贝特医药股份有限公司 | 2022-10-13 | — | — | WO | disclosed |
| EP-0645172-A1 | Method and catalyst for treating exhaust gases containing dioxines | N.E. CHEMCAT CORPORATION (JP) | 1995-03-29 | — | — | EP | disclosed |
| CN-1021330-C | Herbicide containing triazine derivative as active ingredient | IDEMITSU KOSAN CO (JP) | 1993-06-23 | — | — | CN | disclosed |
| US-4863958-A | TREATING ALLERGIC CONDITIONS, ASTHMA, CARDIOVASCULAR DISORDERS, AND INFLAMMATION | MERCK FROSST CANADA, INC. (CA) | 1989-09-05 | — | — | US | disclosed |
| US-4839042-A | POLYOXYALKYLENE GLYCOL AND ALKALI(EARTH) METAL ALCOHOLATE | SEA MARCONI TECHNOLOGIES S.P.A. (IT) | 1989-06-13 | — | — | US | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |
| EP-0135043-B1 | A CONTINUOUS DECONTAMINATION-DECOMPOSITION PROCESS FOR TREATING HALOGENATED ORGANIC COMPOUNDS AND TOXID SUBSTANCES | SEA MARCONI TECHNOLOGIES S.p.a. (IT) | 1987-09-30 | — | — | EP | disclosed |
| CN-86106040-A | Triazine derivatives, process for producing the same and herbicides containing the same as active ingredient | — | 1987-05-20 | — | — | CN | disclosed |
| EP-0135043-A1 | A continuous decontamination-decomposition process for treating halogenated organic compounds and toxid substances | SEA MARCONI TECHNOLOGIES S.p.a. (IT) | 1985-03-27 | — | — | EP | disclosed |
| US-4120937-A | Process for the production of halosilicon acids and organic silicon acid compounds and resinous products | BLOUNT DAVID H | 1978-10-17 | — | — | US | disclosed |
| US-4008266-A | Coupling of aromatic compounds in the presence of molecular oxygen, a mercuric oxyanion compound, and a group VIII metal or group VIII metal oxyanion compound | MONSANTO COMPANY (US) | 1977-02-15 | — | — | US | disclosed |