Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.52 |
| ▸ | SPR | P35270 | 5/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1946155 | 0.80 | SETD7 (0.52) | SETD7SPRSMARCA2SMARCA4PBRM1 | |
| SCHEMBL26669286 | 0.80 | SETD7 (0.52) | SETD7SPRSMARCA2SMARCA4PBRM1 | |
| SCHEMBL1102308 | 0.77 | SETD7 (0.65) | SETD7SPRGPR119HTTL3MBTL1 | |
| SCHEMBL3638878 | 0.77 | SETD7 (0.65) | SETD7SPRGPR119HTTL3MBTL1 | |
| SCHEMBL31155292 | 0.76 | GPR119 (0.44) | SETD7SMARCA2SMARCA4PBRM1GPR119 | |
| SCHEMBL4336794 | 0.76 | SETD7 (0.52) | SETD7SPRSMARCA2SMARCA4PBRM1 | |
| SCHEMBL28878080 | 0.75 | SETD7 (0.66) | SETD7SPRHTTL3MBTL1 | |
| SCHEMBL28878082 | 0.75 | SETD7 (0.66) | SETD7SPRHTTL3MBTL1 | |
| SCHEMBL31169977 | 0.75 | SETD7 (0.47) | SETD7SPRSMARCA2SMARCA4PBRM1 | |
| SCHEMBL19284223 | 0.74 | SETD7 (0.67) | SETD7GPR119LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024199402-A1 | HETEROCYCLIC COMPOUND AS AT2R ANTAGONIST | 武汉人福创新药物研发中心有限公司 | 2024-10-03 | — | — | WO | disclosed |
| CN-118724877-A | Heterocyclic compounds as AT2R antagonists | 武汉人福创新药物研发中心有限公司 | 2024-10-01 | — | — | CN | disclosed |