Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.47 |
| ▸ | SPR | P35270 | 5/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31170653 | 0.86 | ABHD6 (0.43) | SETD7SPRGPR119ABHD6DAGLA | |
| SCHEMBL31170689 | 0.85 | ABHD6 (0.40) | SETD7SPRGPR119ABHD6DAGLA | |
| SCHEMBL31170385 | 0.85 | SPR (0.44) | SETD7SPRSMARCA2SMARCA4PBRM1 | |
| SCHEMBL31170139 | 0.85 | SPR (0.44) | SETD7SPRSMARCA2SMARCA4PBRM1 | |
| SCHEMBL31170462 | 0.82 | ABHD6 (0.42) | GPR119ABHD6DAGLA | |
| SCHEMBL28055264 | 0.80 | SETD7 (0.51) | SETD7SPRSMARCA2SMARCA4PBRM1 | |
| SCHEMBL4336794 | 0.76 | SETD7 (0.52) | SETD7SPRSMARCA2SMARCA4PBRM1 | |
| SCHEMBL31155296 | 0.75 | SETD7 (0.52) | SETD7SPRSMARCA2SMARCA4PBRM1 | |
| SCHEMBL26132034 | 0.75 | HPGD (0.48) | SETD7 | |
| SCHEMBL26132028 | 0.75 | HPGD (0.48) | SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4712961-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024238633-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-11-21 | — | — | WO | disclosed |