Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489916 | 0.81 | HTR2A (0.45) | — | |
| SCHEMBL15609148 | 0.79 | CES2 (0.41) | CES2CES1CA12CA1CA9 | |
| SCHEMBL31155322 | 0.77 | — | — | |
| SCHEMBL22558692 | 0.74 | EPHX1 (0.44) | — | |
| SCHEMBL16861593 | 0.72 | HRH3 (0.38) | CES2CES1 | |
| SCHEMBL18249584 | 0.68 | CES2 (0.40) | CES2CES1 | |
| SCHEMBL19734729 | 0.67 | CCR5 (0.36) | — | |
| SCHEMBL18663529 | 0.67 | SLC6A2 (0.33) | CES2CES1 | |
| SCHEMBL5752497 | 0.67 | CES2 (0.35) | CES2CES1 | |
| SCHEMBL19734693 | 0.66 | CCR5 (0.38) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024199402-A1 | HETEROCYCLIC COMPOUND AS AT2R ANTAGONIST | 武汉人福创新药物研发中心有限公司 | 2024-10-03 | — | — | WO | disclosed |
| CN-118724877-A | Heterocyclic compounds as AT2R antagonists | 武汉人福创新药物研发中心有限公司 | 2024-10-01 | — | — | CN | disclosed |