Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | USP1 | O94782 | 8/20 | 0.36 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31155983 | 0.86 | USP1 (0.41) | USP1STIM1ORAI1TSHRKDM4E | |
| SCHEMBL30462037 | 0.84 | STIM1 (0.39) | CCR1USP1STIM1ORAI1TSHR | |
| SCHEMBL31155907 | 0.80 | USP1 (0.38) | USP1PTGS2PTGS1 | |
| SCHEMBL31155897 | 0.77 | STIM1 (0.42) | CCR1USP1STIM1ORAI1TSHR | |
| SCHEMBL26627832 | 0.74 | CCR1 (0.45) | CCR1USP1STIM1ORAI1TSHR | |
| SCHEMBL31155882 | 0.74 | PTGS2 (0.49) | CCR1STIM1ORAI1PTGS2PTGS1 | |
| SCHEMBL31155958 | 0.72 | USP1 (0.48) | USP1STIM1ORAI1TSHRPTGS2 | |
| SCHEMBL31423591 | 0.71 | PDE4A (0.40) | USP1STIM1ORAI1TSHRKDM4E | |
| SCHEMBL31423506 | 0.71 | APP (0.36) | STIM1ORAI1TSHRKDM4EALDH1A1 | |
| SCHEMBL31537663 | 0.71 | USP1 (0.43) | USP1TSHRALDH1A1MAPTWDR48 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208292-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 INHIBITOR, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2024-10-10 | — | — | WO | disclosed |