Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382994 | 0.87 | NPSR1 (0.59) | KMT2AMEN1NPSR1KDM4EMAPT | |
| SCHEMBL31156465 | 0.82 | NPSR1 (0.56) | KMT2AMEN1NPSR1KDM4EMAPT | |
| SCHEMBL8347159 | 0.73 | ALDH1A1 (0.49) | KMT2AMEN1NPSR1KDM4EMAPT | |
| SCHEMBL9640969 | 0.72 | KMT2A (0.53) | KMT2AMEN1NPSR1KDM4EMAPT | |
| SCHEMBL15955611 | 0.71 | KMT2A (0.56) | KMT2AMEN1NPSR1KDM4EMAPT | |
| SCHEMBL6441907 | 0.69 | ALDH1A1 (0.52) | KMT2AMEN1NPSR1KDM4EMAPT | |
| SCHEMBL31156502 | 0.69 | NPSR1 (0.57) | KMT2AMEN1NPSR1KDM4EMAPT | |
| SCHEMBL13386295 | 0.69 | KMT2A (0.69) | KMT2AMEN1NPSR1KDM4EHTT | |
| SCHEMBL31156478 | 0.69 | ALDH1A1 (0.57) | KMT2AMEN1NPSR1KDM4EMAPT | |
| SCHEMBL20011841 | 0.67 | MEN1 (0.49) | KMT2AMEN1MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013280-A | Compound for regulating 15-PGDH activity and preparation method thereof | 赛诺哈勃药业（成都）有限公司 | 2024-11-22 | — | — | CN | disclosed |