Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | DHPS | P49366 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382994 | 0.80 | NPSR1 (0.59) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL4767221 | 0.78 | HPGD (0.47) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL8348946 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL31156489 | 0.73 | KMT2A (0.58) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL6445364 | 0.73 | ADORA1 (0.65) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL8347394 | 0.72 | KMT2A (0.61) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL10379122 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL15955611 | 0.71 | KMT2A (0.56) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL4787898 | 0.71 | FOS (0.44) | ALDH1A1TSHRHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL9640969 | 0.69 | KMT2A (0.53) | ALDH1A1MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024159-A1 | INHIBITORS OF TFGβ | SCIOS INC. (US) | 2004-03-25 | — | — | WO | disclosed |