Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31157581 | 0.99 | ELANE (0.38) | ELANELMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL30298051 | 0.98 | ELANE (0.35) | ELANELMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL30298089 | 0.86 | PIK3CG (0.38) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL30298044 | 0.83 | GRM4 (0.34) | ELANEXDHKDM4ERECQL | |
| SCHEMBL31157566 | 0.79 | NAMPT (0.35) | ELANELMNAKMT2ANAMPTKDM4E | |
| SCHEMBL30297993 | 0.76 | ELANE (0.39) | ELANELMNAKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL31157590 | 0.76 | HRH1 (0.38) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL31157482 | 0.76 | FNTA (0.39) | KMT2AKDM4EPIK3CG | |
| SCHEMBL31157397 | 0.75 | PIK3CG (0.45) | LMNAKMT2AKDM4EPIK3CG | |
| SCHEMBL31157532 | 0.74 | LMNA (0.43) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376100-A1 | PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1, 4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES | Redona Therapeutics, Inc. | 2024-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376100-A1 | PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1, 4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES | PAPSS1, OTUD7B, BRD7 | ELANE 3603/4885LMNA 3801/4885CYP2C9 2150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.