SCHEMBL31157482

SCHEMBL31157482

CC(C)(C)OC(=O)N1CCC(Cn2cc(C(=O)O)c(=O)c3cc(Cl)c(N4Cc5cccnc5C4)nc32)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 2/20 0.39
▸ FNTB P49356 2/20 0.39
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ PIK3CG P48736 1/20 0.37
▸ USP7 Q93009 2/20 0.37
▸ POLB P06746 1/20 0.37
▸ NPSR1 Q6W5P4 2/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ TDP1 Q9NUW8 2/20 0.36
▸ USP2 O75604 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ GPR119 Q8TDV5 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31157508 0.88 PIK3CG (0.41) FNTAFNTBMEN1KMT2APIK3CG
Hydrochloric Acid SCHEMBL31157590 0.85 HRH1 (0.38) PIK3CGNPSR1KDM4ETDP1HRH1
SCHEMBL31157490 0.79 LMNA (0.39) MEN1KMT2APIK3CGNPSR1KDM4E
SCHEMBL31157532 0.79 LMNA (0.43) PIK3CGNPSR1KDM4ETDP1TSHR
SCHEMBL31157592 0.78 LMNA (0.37) PIK3CGNPSR1KDM4ETDP1TSHR
SCHEMBL31157518 0.78 GAA (0.43) MEN1KMT2APIK3CGPOLBNPSR1
SCHEMBL31157378 0.78 CHRM1 (0.48) POLBKDM4EALDH1A1HPGDTSHR
SCHEMBL31157568 0.77 KDM4E (0.45) PIK3CGNPSR1KDM4ETDP1ALDH1A1
SCHEMBL31157576 0.77 GAA (0.37) PIK3CGPOLBNPSR1KDM4ETDP1
SCHEMBL31157544 0.77 LMNA (0.37) MEN1KMT2APIK3CGNPSR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376100-A1 PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1, 4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES Redona Therapeutics, Inc. 2024-11-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376100-A1 PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1, 4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES PAPSS1, OTUD7B, BRD7 FNTA 4740/4885FNTB 4720/4885MEN1 3213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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