Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24570919 | 0.78 | SRD5A1 (0.44) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL31158034 | 0.78 | SRD5A1 (0.44) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL2571011 | 0.76 | SRD5A1 (0.48) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL2571280 | 0.76 | SRD5A1 (0.48) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL2572769 | 0.76 | SRD5A1 (0.48) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL31158032 | 0.76 | SRD5A1 (0.42) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL24570929 | 0.76 | SRD5A1 (0.42) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL13948754 | 0.75 | SRD5A1 (0.49) | SRD5A1OPRM1OPRD1OPRK1PDK1 | |
| SCHEMBL25831640 | 0.75 | SRD5A1 (0.49) | SRD5A1OPRM1OPRD1OPRK1PDK1 | |
| SCHEMBL10024954 | 0.75 | SRD5A1 (0.49) | SRD5A1OPRM1OPRD1OPRK1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385035-B1 | PREPARATION METHOD OF DIHYDROINDENE AMIDE COMPOUNDS THEIR PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS THEREOF AND USE AS PROTEIN KINASES INHIBITOR | HARBIN GLORIA PHARMACEUTICALS CO LTD (CN) | 2014-06-25 | — | — | EP | disclosed |
| US-8703771-B2 | Preparation method of dihydroindene amide compounds, their pharmaceutical compositions containing compounds thereof and use as protein kinases inhibitor | HARBIN GLORIA PHARMACEUTICALS CO., LTD. (CN) | 2014-04-22 | — | — | US | disclosed |
| US-20110319420-A1 | PREPARATION METHOD OF DIHYDROINDENE AMIDE COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS THEREOF AND USE AS PROTEIN KINASES INHIBITOR | HARBIN GLORIA PHARMACEUTICALS CO., LTD (CN) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319420-A1 | PREPARATION METHOD OF DIHYDROINDENE AMIDE COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS THEREOF AND USE AS PROTEIN KINASES INHIBITOR | KIT, ABL1, ABL2 | SRD5A1 3738/4885CCR5 2278/4885OPRM1 4104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.