Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769880 | 0.75 | LMNA (0.40) | HTTKDM4ELMNACNR1CNR2 | |
| SCHEMBL30356454 | 0.73 | EZH2 (0.46) | EZH2 | |
| SCHEMBL13280122 | 0.73 | EZH2 (0.46) | EZH2 | |
| SCHEMBL13451052 | 0.71 | GAA (0.52) | TP53KDM4EPARP1CNR2F2 | |
| SCHEMBL31158037 | 0.69 | EZH2 (0.39) | EZH2HTTKDM4E | |
| SCHEMBL30777398 | 0.69 | PARP1 (0.39) | EZH2KDM4EOPRK1KCNH2HTR1A | |
| SCHEMBL39964 | 0.68 | KDM4E (0.52) | KDM4EPARP1 | |
| SCHEMBL1719653 | 0.67 | KDM4E (0.61) | KDM4EHTR1ALMNAPARP1 | |
| SCHEMBL31158045 | 0.67 | EZH2 (0.40) | EZH2KDM4EOPRK1 | |
| SCHEMBL20409103 | 0.67 | EZH2 (0.40) | EZH2KDM4EOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118745144-A | Novel EZH2 inhibitor compound, and preparation method and application thereof | 辽宁大学 | 2024-10-08 | — | — | CN | disclosed |