Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769889 | 0.85 | HTT (0.39) | LMNAALDH1A1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL31158044 | 0.75 | EZH2 (0.40) | LMNAHTTKDM4ECNR1CNR2 | |
| SCHEMBL21769744 | 0.72 | TP53 (0.36) | ALDH1A1TSHRSMN1; SMN2HTTKDM4E | |
| SCHEMBL29031636 | 0.71 | CNR2 (0.49) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL13090981 | 0.70 | ALDH1A1 (0.47) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL9419140 | 0.65 | LMNA (0.44) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL11589439 | 0.65 | ALDH1A1 (0.47) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL11404688 | 0.64 | ALDH1A1 (0.38) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL4300630 | 0.62 | TRPA1 (0.39) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL29873769 | 0.62 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |