Sarafloxacin

Sarafloxacin

SCHEMBL311593

O=C(O)c1cn(-c2ccc(F)cc2)c2cc(N3CCNCC3)c(F)cc2c1=O

nearest known ligand 0.98

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.98
KDM4E B2RXH2 7/20 0.98
LMNA P02545 5/20 0.98
HSD17B10 Q99714 5/20 0.98
HPGD P15428 4/20 0.98
MEN1 O00255 1/20 0.78
KMT2A Q03164 1/20 0.78
TOP2A P11388 4/20 0.65
TOP2B Q02880 3/20 0.65
CYP1A2 P05177 1/20 0.65
CYP2C9 P11712 1/20 0.65
BRD4 O60885 1/20 0.65
TSHR P16473 1/20 0.65
HTT P42858 1/20 0.65
CYP2J2 P51589 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65
POLB P06746 1/20 0.51
HSP90AA1 P07900 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
TOP1 P11387 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sarafloxacin SCHEMBL379212 0.99 ALDH1A1 (1.00) ALDH1A1KDM4ELMNAHSD17B10HPGD
Sarafloxacin SCHEMBL23392485 0.98 ALDH1A1 (0.98) ALDH1A1KDM4ELMNAHSD17B10HPGD
Sarafloxacin SCHEMBL312072 0.98 ALDH1A1 (0.94) ALDH1A1KDM4ELMNAHSD17B10HPGD
SCHEMBL9443539 0.93 ALDH1A1 (0.85) ALDH1A1KDM4ELMNAHSD17B10HPGD
SCHEMBL9443495 0.93 ALDH1A1 (0.85) ALDH1A1KDM4ELMNAHSD17B10HPGD
SCHEMBL9443455 0.92 ALDH1A1 (0.83) ALDH1A1KDM4ELMNAHSD17B10HPGD
SCHEMBL9044286 0.92 ALDH1A1 (0.83) ALDH1A1KDM4ELMNAHSD17B10HPGD
SCHEMBL9443514 0.92 ALDH1A1 (0.83) ALDH1A1KDM4ELMNAHSD17B10HPGD
SCHEMBL11017466 0.92 ALDH1A1 (0.83) ALDH1A1KDM4ELMNAHSD17B10HPGD
SCHEMBL9443467 0.90 ALDH1A1 (0.80) ALDH1A1KDM4ELMNAHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2328 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094963-A Cardioprotective lipids and methods of use 2026-05-26 CN claimed
US-12624057-B2 Bisphosphonate quinolone conjugates and uses thereof BIOVINC, LLC (US) 2026-05-12 US claimed
US-12350281-B2 Long-acting injectable formulations and use thereof DECHRA VETERINARY PRODUCTS, LLC (US) 2025-07-08 US claimed
CN-120195301-A Method and system for detecting various antibiotics in water based on artificial intelligence 广东中加检测技术股份有限公司 2025-06-24 CN claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
EP-4554627-A1 INHALABLE FORMULATION FOR USE IN THE TREATMENT OF BACTERIAL LUNG INFECTIONS Solmic Biotech GmbH (DE) 2025-05-21 EP claimed
CN-118465254-B Aptamer, enzyme and MOF hybridization-based sarafloxacin stimulus-responsive hydrogel colorimetric sensor 江南大学 2025-05-16 CN claimed
US-20250144088-A1 INHALABLE FORMULATION FOR USE IN THE TREATMENT OF BACTERIAL LUNG INFECTIONS Solmic Biotech GmbH (DE) 2025-05-08 US claimed
CN-119915935-A Synchronous detection method for 42 antibiotics in river mouth multi-environment medium 华东师范大学 2025-05-02 CN claimed
CN-119841958-A Nanometer antibody for broad-spectrum identification of quinolone medicines, and preparation method and application thereof 中国农业大学 2025-04-18 CN claimed
WO-2000050009-A1 METHODS FOR ADMINISTERING PHARMACOLOGICALLY ACTIVE COMPOUNDS TO VERTEBRATES IDEXX LABORATORIES, INC. (US) 2000-08-31 WO claimed
WO-2000032196-A2 INHIBITORS OF MULTIDRUG TRANSPORTERS INFLUX, INC. (US) 2000-06-08 WO claimed
CN-1209065-A Otic microbial combinations BAYER AG (US) 1999-02-24 CN claimed
EP-0869795-A1 OTIC MICROBIAL COMBINATIONS Bayer Corporation (US) 1998-10-14 EP claimed
US-5756506-A ADMINISTERING TO ANIMALS IN TREATMENT OF BACTERIAL INFECTIONS BAYER CORPORATION (US) 1998-05-26 US claimed
EP-0443381-B2 Effervescent composition, its production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1997-10-22 EP claimed
WO-1997024128-A1 OTIC MICROBIAL COMBINATIONS BAYER CORPORATION (US) 1997-07-10 WO claimed
US-5284776-A Complexing with an iron salt and comparing the color to that of a known concentration; kits; veterinary medicine; adjusting the dosage in poultry drinking water ABBOTT LABORATORIES (US) 1994-02-08 US claimed
US-5223246-A Powdered mixture of antibacterial oxo-carboxylic acids having fused nitrogen rings, carbonates, water soluble binders, for treatment of drinking water for livestock TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-06-29 US claimed
EP-0443381-A1 Effervescent composition, its production and use Takeda Chemical Industries, Ltd. (JP) 1991-08-28 EP claimed