Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20121418 | 0.81 | MAPT (0.46) | POLBHPGDNPSR1KDM4EALDH1A1 | |
| SCHEMBL31159930 | 0.78 | KMT2A (0.37) | HPGDNPSR1KDM4EALDH1A1KMT2A | |
| SCHEMBL23971107 | 0.75 | CA12 (0.46) | HPGDHTTKDM4EALDH1A1KMT2A | |
| SCHEMBL10682199 | 0.75 | MAPT (0.51) | POLBHPGDNPSR1KDM4EALDH1A1 | |
| SCHEMBL27255559 | 0.71 | KDM4E (0.45) | POLBHPGDNPSR1KDM4EALDH1A1 | |
| SCHEMBL19826010 | 0.69 | CA12 (0.55) | HTTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL23159630 | 0.69 | CNR2 (0.48) | POLBHPGDNPSR1KDM4EALDH1A1 | |
| SCHEMBL10676568 | 0.69 | MAPT (0.49) | POLBHPGDNPSR1KDM4EALDH1A1 | |
| SCHEMBL18940647 | 0.68 | KDM4E (0.49) | POLBHPGDNPSR1HTTKDM4E | |
| SCHEMBL27255581 | 0.68 | ALDH1A1 (0.39) | NPSR1KDM4EALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688144-A1 | COMPOUNDS AS GLP-1R AGONISTS | Terns Pharmaceuticals, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024206878-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2024-10-03 | — | — | WO | disclosed |