SCHEMBL31160486

SCHEMBL31160486

Cc1ccc(-c2c(C#Cc3ccccc3)c3cccnc3n2S(=O)(=O)c2ccccc2)c(-c2ccccc2)c1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 10/20 0.42
CKS1B P61024 1/20 0.38
SKP2 Q13309 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.35
AGTR1 P30556 1/20 0.35
PDE4A P27815 1/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35
CCKAR P32238 1/20 0.35
GRM4 Q14833 1/20 0.34
LATS1 O95835 1/20 0.34
ELANE P08246 1/20 0.34
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31160497 0.90 PTGDR2 (0.38) PTGDR2CKS1BSKP2L3MBTL1AGTR1
SCHEMBL31160484 0.83 PTGDR2 (0.46) PTGDR2CKS1BSKP2L3MBTL1AGTR1
SCHEMBL31160496 0.74 L3MBTL1 (0.46) PTGDR2CKS1BSKP2L3MBTL1CYP2C19
SCHEMBL31160494 0.70 COPS5 (0.40) CKS1BSKP2GRM4
SCHEMBL31160459 0.68 L3MBTL1 (0.42) PTGDR2CKS1BSKP2L3MBTL1LATS1
SCHEMBL13505139 0.67 PTGDR2 (0.46) PTGDR2CKS1BSKP2L3MBTL1AGTR1
SCHEMBL1773016 0.66 PTGDR2 (0.67) PTGDR2CCKARLATS1CYP2C19
SCHEMBL8944259 0.65 L3MBTL1 (0.67) PTGDR2CKS1BSKP2L3MBTL1AGTR1
SCHEMBL1778795 0.65 PTGDR2 (0.46) PTGDR2CKS1BSKP2L3MBTL1AGTR1
SCHEMBL31160500 0.65 CKS1B (0.41) PTGDR2CKS1BSKP2L3MBTL1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019389-B 7-Azaindole compound and synthetic method and application thereof SICHUAN UNIVERSITY (CN) 2026-05-26 CN disclosed
CN-119019389-A 7-Azaindole compound and synthetic method and application thereof 四川大学 2024-11-26 CN disclosed