SCHEMBL31160484

SCHEMBL31160484

Cc1ccc(-c2c(I)c3cccnc3n2S(=O)(=O)c2ccccc2)c(-c2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 11/20 0.46
CKS1B P61024 2/20 0.41
SKP2 Q13309 2/20 0.41
CCKAR P32238 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
AGTR1 P30556 1/20 0.38
LATS1 O95835 1/20 0.36
CYP2C19 P33261 1/20 0.36
POLB P06746 1/20 0.36
ALDH3A1 P30838 1/20 0.36
HTT P42858 1/20 0.36
NOD1 Q9Y239 1/20 0.36
GLO1 Q04760 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31160486 0.83 PTGDR2 (0.42) PTGDR2CKS1BSKP2CCKARL3MBTL1
SCHEMBL31160497 0.78 PTGDR2 (0.38) PTGDR2CKS1BSKP2L3MBTL1AGTR1
SCHEMBL31160496 0.78 L3MBTL1 (0.46) PTGDR2CKS1BSKP2L3MBTL1CYP2C19
SCHEMBL4583577 0.77 PTGDR2 (0.64) PTGDR2CCKARLATS1CYP2C19
SCHEMBL1778795 0.73 PTGDR2 (0.46) PTGDR2CKS1BSKP2L3MBTL1AGTR1
SCHEMBL4583261 0.72 PTGDR2 (0.51) PTGDR2LATS1CYP2C19
SCHEMBL20005127 0.72 PTGDR2 (0.57) PTGDR2CCKARL3MBTL1LATS1CYP2C19
SCHEMBL31160459 0.71 L3MBTL1 (0.42) PTGDR2CKS1BSKP2L3MBTL1LATS1
SCHEMBL13505139 0.71 PTGDR2 (0.46) PTGDR2CKS1BSKP2L3MBTL1AGTR1
SCHEMBL1773016 0.69 PTGDR2 (0.67) PTGDR2CCKARLATS1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019389-B 7-Azaindole compound and synthetic method and application thereof SICHUAN UNIVERSITY (CN) 2026-05-26 CN disclosed
CN-119019389-A 7-Azaindole compound and synthetic method and application thereof 四川大学 2024-11-26 CN disclosed