Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | DTYMK | P23919 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226358 | 1.00 | GRM5 (0.43) | GRM5PDE10AGPR119USP30DTYMK | |
| SCHEMBL5226349 | 1.00 | GRM5 (0.43) | GRM5PDE10AGPR119USP30DTYMK | |
| SCHEMBL5226353 | 1.00 | GRM5 (0.43) | GRM5PDE10AGPR119USP30DTYMK | |
| SCHEMBL4763188 | 0.90 | ALDH1A1 (0.43) | GRM5PDE10AGPR119USP30DTYMK | |
| SCHEMBL5230017 | 0.85 | STS (0.43) | GPR119USP30ACHECYP11B2 | |
| SCHEMBL5229997 | 0.85 | STS (0.43) | GPR119USP30ACHECYP11B2 | |
| SCHEMBL5230008 | 0.85 | STS (0.43) | GPR119USP30ACHECYP11B2 | |
| SCHEMBL5226196 | 0.80 | MAPK1 (0.44) | GRM5PDE10AGPR119USP30DTYMK | |
| SCHEMBL6333649 | 0.79 | DDB1 (0.38) | USP30MAPTCYP11B2 | |
| SCHEMBL6699701 | 0.78 | GPR119 (0.41) | GRM5PDE10AGPR119USP30DTYMK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024217441-A1 | GHSR 1A AGONIST, PHARMACEUTICAL COMPOSITION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 长春金赛药业有限责任公司 | 2024-10-24 | — | — | WO | disclosed |