Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB3 | P54753 | 6/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KIF18A | Q8NI77 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31167149 | 0.85 | IRAK4 (0.52) | IRAK4KIF18A | |
| SCHEMBL31167184 | 0.83 | KIF18A (0.57) | KIF18A | |
| SCHEMBL31167155 | 0.82 | EPHB3 (0.43) | EPHB3IRAK4LMNAHTTKIF18A | |
| SCHEMBL31167082 | 0.82 | KIF18A (0.63) | KIF18A | |
| SCHEMBL31018593 | 0.75 | KIF18A (0.40) | KIF18A | |
| SCHEMBL30842149 | 0.74 | KIF18A (0.49) | KIF18A | |
| SCHEMBL30856579 | 0.74 | KIF18A (0.49) | KIF18A | |
| SCHEMBL30600578 | 0.74 | KIF18A (0.41) | KIF18A | |
| SCHEMBL30856596 | 0.73 | KIF18A (0.44) | IRAK4KIF18A | |
| SCHEMBL30842137 | 0.73 | KIF18A (0.50) | KIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978521-A | Preparation method and application of fused ring compound | 江苏普莱医药生物技术有限公司 | 2024-11-19 | — | — | CN | disclosed |