Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31168519 | 0.78 | S100A9 (0.38) | CYP11B1CYP11B2KCNJ5KCNJ3 | |
| SCHEMBL31168516 | 0.78 | S100A9 (0.38) | CYP11B1CYP11B2KCNJ5KCNJ3 | |
| SCHEMBL31168484 | 0.78 | GCK (0.36) | KCNJ5KCNJ3 | |
| SCHEMBL4973249 | 0.75 | AGBL2 (0.41) | AGBL2 | |
| SCHEMBL31168603 | 0.70 | AGBL2 (0.42) | AGBL2CYP11B1CYP11B2CA2 | |
| SCHEMBL19304135 | 0.68 | AGBL2 (0.39) | AGBL2 | |
| SCHEMBL30286760 | 0.66 | — | — | |
| SCHEMBL31168607 | 0.66 | — | — | |
| SCHEMBL134813 | 0.66 | AGBL2 (0.43) | AGBL2 | |
| SCHEMBL29941432 | 0.66 | AGBL2 (0.43) | AGBL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024216164-A1 | N2-((5-HYDROXY)-2-PYRIDYL)-PYRIDINE-2,4-DIAMINE DERIVATIVES AS EHMT1/2 MODULATORS FOR THE TREATMENT OF CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-10-17 | — | — | WO | disclosed |