Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22412040 | 1.00 | CREBBP (0.36) | CREBBPLMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL22412042 | 1.00 | CREBBP (0.36) | CREBBPLMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL22411874 | 0.83 | CREBBP (0.37) | CREBBPLMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL28665584 | 0.80 | CREBBP (0.35) | CREBBPCYP3A4CYP2C9GAAMEN1 | |
| SCHEMBL29684374 | 0.79 | PPARA (0.35) | CREBBPGAAMEN1KMT2A | |
| SCHEMBL28665586 | 0.79 | PPARA (0.35) | CREBBPGAAMEN1KMT2A | |
| SCHEMBL22411925 | 0.76 | CREBBP (0.46) | CREBBPLMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL22411798 | 0.76 | CREBBP (0.43) | CREBBPLMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL24496971 | 0.71 | ALDH1A1 (0.36) | LMNAHTTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL29711836 | 0.71 | ALDH1A1 (0.36) | LMNAHTTALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113811534-B | TYK2 inhibitors and uses thereof | 阿鲁米斯公司 | 2024-10-29 | — | — | CN | disclosed |