Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22290716 | 1.00 | KMT2A (0.37) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL22290836 | 0.87 | HDAC1 (0.39) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL22306174 | 0.85 | HDAC1 (0.41) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL22290446 | 0.84 | POLB (0.44) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL22290419 | 0.83 | ALDH1A1 (0.40) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL31173155 | 0.83 | ALDH1A1 (0.40) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL30315938 | 0.83 | HDAC3 (0.44) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL22290429 | 0.80 | TRPA1 (0.41) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL31173245 | 0.80 | TRPA1 (0.41) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL22290536 | 0.80 | TRPA1 (0.39) | KMT2AMEN1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113645971-B | Compounds and uses thereof | 福宏治疗公司 | 2024-10-18 | — | — | CN | disclosed |