Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22290716 | 0.85 | KMT2A (0.37) | HDAC1HDAC2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL22290419 | 0.85 | ALDH1A1 (0.40) | HDAC1HDAC2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL31173155 | 0.85 | ALDH1A1 (0.40) | HDAC1HDAC2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL31173442 | 0.85 | KMT2A (0.37) | HDAC1HDAC2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL22290836 | 0.83 | HDAC1 (0.39) | HDAC1HDAC2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL31173274 | 0.80 | MEN1 (0.42) | ALDH1A1KMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL22290392 | 0.80 | MEN1 (0.42) | ALDH1A1KMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL22305489 | 0.80 | MAPT (0.52) | HDAC1HDAC2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL22305493 | 0.80 | MAPT (0.47) | HDAC1HDAC2ALDH1A1KMT2AMEN1 | |
| SCHEMBL22290429 | 0.79 | TRPA1 (0.41) | ALDH1A1KMT2ASMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |