SCHEMBL311736

SCHEMBL311736

CC(C)(C)c1ccc(-c2cc3c4cc(-c5ccc(C(C)(C)C)cc5)c(-c5ccc(C(C)(C)C)cc5)cc4c4cc(-c5ccc(C(C)(C)C)cc5)c(-c5ccc(C(C)(C)C)cc5)cc4c3cc2-c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.48
TSHR P16473 1/20 0.46
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
LMNA P02545 2/20 0.46
TP53 P04637 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
DGAT1 O75907 2/20 0.44
TYR P14679 1/20 0.44
ALDH1A1 P00352 2/20 0.41
MITF O75030 1/20 0.41
KMT2A Q03164 1/20 0.41
GPR84 Q9NQS5 1/20 0.41
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21037516 0.87 KIF11 (0.42) KIF11TSHRNPC1RAB9ALMNA
SCHEMBL380068 0.87 KIF11 (0.47) KIF11TSHRNPC1RAB9ALMNA
SCHEMBL31047817 0.79 NPC1 (0.50) KIF11TSHRNPC1RAB9ALMNA
SCHEMBL26915 0.78 KIF11 (0.70) KIF11TSHRNPC1RAB9ALMNA
SCHEMBL3423876 0.78 KIF11 (0.70) KIF11TSHRNPC1RAB9ALMNA
SCHEMBL3680164 0.78 KIF11 (0.42) KIF11TSHRNPC1RAB9ALMNA
SCHEMBL7240621 0.78 NPC1 (0.49) KIF11TSHRNPC1RAB9ALMNA
SCHEMBL12126697 0.76 GPR84 (0.40) KIF11LMNASMN1; SMN2KMT2AGPR84
SCHEMBL29404863 0.76 TSHR (0.48) KIF11TSHRNPC1RAB9ALMNA
SCHEMBL30395197 0.76 KIF11 (0.57) KIF11TSHRNPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3064563-B1 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2018-12-26 EP disclosed
EP-3064563-A1 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2016-09-07 EP disclosed
US-9139494-B2 Triphenylene hosts in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2015-09-22 US disclosed
US-8580404-B2 Triphenylene hosts in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2013-11-12 US disclosed
US-20130001538-A1 Triphenylene Hosts in Phosphorescent Light Emitting Diodes UNIVERSAL DISPLAY CORPORATION (US) 2013-01-03 US disclosed
EP-1888708-B1 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2012-11-21 EP disclosed
US-20120032156-A1 Triphenylene Hosts in Phosphorescent Light Emitting Diodes UNIVERSAL DISPLAY CORPORATION 2012-02-09 US disclosed
US-8092924-B2 Triphenylene hosts in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2012-01-10 US disclosed
EP-2277978-A2 Triphenylene hosts in phosphorescent light emitting diodes Universal Display Corporation (US) 2011-01-26 EP disclosed
US-20060280965-A1 Triphenylene hosts in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION 2006-12-14 US disclosed