Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311736 | 0.87 | KIF11 (0.48) | KIF11NPC1RAB9ALMNATP53 | |
| SCHEMBL25677937 | 0.77 | KIF11 (0.43) | KIF11NPC1RAB9ALMNATP53 | |
| SCHEMBL30304254 | 0.76 | ALDH1A1 (0.43) | KIF11NPC1RAB9ALMNATSHR | |
| SCHEMBL285463 | 0.76 | ALDH1A1 (0.43) | KIF11NPC1RAB9ALMNATSHR | |
| SCHEMBL13433265 | 0.76 | ALDH1A1 (0.43) | KIF11NPC1RAB9ALMNATSHR | |
| SCHEMBL31442918 | 0.75 | KIF11 (0.42) | KIF11NPC1RAB9ALMNATP53 | |
| SCHEMBL380068 | 0.75 | KIF11 (0.47) | KIF11NPC1RAB9ALMNATP53 | |
| SCHEMBL1823358 | 0.75 | KIF11 (0.42) | KIF11NPC1RAB9ALMNATP53 | |
| SCHEMBL28159071 | 0.73 | KIF11 (0.37) | KIF11NPC1RAB9ALMNATP53 | |
| SCHEMBL13321283 | 0.73 | KIF11 (0.37) | KIF11NPC1RAB9ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11639339-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-05-02 | — | — | US | disclosed |
| US-11639339-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-05-02 | — | — | US | disclosed |
| WO-2019101835-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11639339-B2 | Materials for organic electroluminescent devices | L1CAM, EFNA1, EPCAM | KIF11 2414/4885NPC1 2041/4885RAB9A 2567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.