Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28586149 | 1.00 | NOTUM (0.51) | NOTUMHTTEPHX2ALDH1A1MEN1 | |
| SCHEMBL28600058 | 0.81 | KEAP1 (0.44) | NOTUMALDH1A1POLBGAAMAPT | |
| SCHEMBL31174786 | 0.81 | KEAP1 (0.44) | NOTUMALDH1A1POLBGAAMAPT | |
| SCHEMBL22897566 | 0.78 | NOTUM (0.55) | NOTUMHTTEPHX2ALDH1A1MAPT | |
| SCHEMBL20320415 | 0.78 | NOTUM (0.55) | NOTUMHTTEPHX2ALDH1A1POLB | |
| SCHEMBL10360314 | 0.78 | EPHX2 (0.56) | NOTUMHTTEPHX2ALDH1A1MEN1 | |
| SCHEMBL44807 | 0.78 | NOTUM (0.55) | NOTUMHTTEPHX2ALDH1A1MEN1 | |
| SCHEMBL21816148 | 0.76 | P2RX7 (0.46) | NOTUMALDH1A1MEN1POLBMAPT | |
| SCHEMBL21816146 | 0.76 | KMT2A (0.55) | NOTUMHTTEPHX2ALDH1A1MEN1 | |
| SCHEMBL18003702 | 0.75 | ALDH1A1 (0.55) | NOTUMHTTEPHX2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164458-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-113164458-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-13 | — | — | CN | disclosed |