SCHEMBL31177366

SCHEMBL31177366

CCCCCC(=CS(=O)(=O)c1ccc(C)cc1)S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 1/20 0.43
MCHR1 Q99705 1/20 0.41
ALDH1A1 P00352 7/20 0.41
CYP2C9 P11712 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
LMNA P02545 1/20 0.40
ALB P02768 1/20 0.40
TSHR P16473 1/20 0.40
RAB9A P51151 2/20 0.39
KMT2A Q03164 2/20 0.39
CNR2 P34972 2/20 0.39
CTSK P43235 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C19 P33261 2/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
MAPT P10636 2/20 0.36
NPC1 O15118 1/20 0.36
NFKB1 P19838 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10889930 0.81 PTGS2 (0.41) ALDH1A1CYP2C9TDP1LMNAKMT2A
SCHEMBL28433005 0.81 TLR9 (0.44) TLR9MCHR1ALDH1A1CYP2C9TDP1
SCHEMBL8472264 0.78 TLR9 (0.42) TLR9MCHR1ALDH1A1CYP2C9TDP1
SCHEMBL11410505 0.73 ALDH1A1 (0.41) MCHR1ALDH1A1CYP2C9TDP1LMNA
SCHEMBL10911801 0.72 TLR9 (0.57) TLR9ALDH1A1CYP2C9TDP1LMNA
SCHEMBL8472266 0.72 MCHR1 (0.42) MCHR1ALDH1A1CYP2C9TDP1LMNA
SCHEMBL11401049 0.71 ALDH1A1 (0.43) MCHR1ALDH1A1CYP2C9TDP1LMNA
SCHEMBL11411787 0.71 ALDH1A1 (0.43) MCHR1ALDH1A1CYP2C9TDP1LMNA
SCHEMBL11401047 0.71 ALDH1A1 (0.43) MCHR1ALDH1A1CYP2C9TDP1LMNA
SCHEMBL7878733 0.71 TLR9 (0.52) TLR9MCHR1ALDH1A1CYP2C9TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118791409-A Synthesis method of trans-1, 2-di-p-toluenesulfonyl vinyl compound 广东工业大学 2024-10-18 CN disclosed