Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC42 | P60953 | 3/20 | 0.43 |
| ▸ | RAC1 | P63000 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580243 | 0.66 | CDC42 (0.49) | CDC42RAC1PTGS2PTGS1NPC1 | |
| P-Hydroxy Ketorolac SCHEMBL17369576 | 0.65 | PTGS2 (0.79) | CDC42RAC1PTGS2PTGS1NPC1 | |
| P-Hydroxy Ketorolac SCHEMBL17378052 | 0.65 | PTGS2 (0.79) | CDC42RAC1PTGS2PTGS1NPC1 | |
| SCHEMBL14577657 | 0.64 | PTGS2 (0.76) | CDC42RAC1PTGS2PTGS1NPC1 | |
| SCHEMBL11604699 | 0.64 | PTGS2 (0.56) | CDC42RAC1PTGS2PTGS1NPC1 | |
| SCHEMBL10398047 | 0.64 | NPC1 (0.53) | CDC42RAC1PTGS2PTGS1NPC1 | |
| SCHEMBL11265451 | 0.64 | CDC42 (0.60) | CDC42RAC1PTGS2PTGS1NPC1 | |
| SCHEMBL11603510 | 0.64 | CDC42 (0.60) | CDC42RAC1PTGS2PTGS1NPC1 | |
| SCHEMBL10934380 | 0.63 | CDC42 (0.59) | CDC42RAC1PTGS2PTGS1NPC1 | |
| SCHEMBL11064934 | 0.63 | CDC42 (0.49) | CDC42RAC1PTGS2PTGS1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720040-A1 | SULFONAMIDE COMPOUNDS BENEFICIAL IN NEUROPROTECTIVE TREATMENT | Lario Therapeutics Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246522-A1 | SULFONAMIDE COMPOUNDS BENEFICIAL IN NEUROPROTECTIVE TREATMENT | LARIO THERAPEUTICS LIMITED (GB) | 2024-12-05 | — | — | WO | disclosed |