Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128372 | 0.85 | L3MBTL1 (0.41) | PDE4BPDE4DPDE4APDE4CL3MBTL1 | |
| SCHEMBL3122747 | 0.81 | PDE4B (0.47) | PDE4BPDE4DPDE4APDE4CL3MBTL1 | |
| SCHEMBL3126008 | 0.80 | MAPT (0.43) | L3MBTL1 | |
| SCHEMBL3120994 | 0.79 | L3MBTL1 (0.39) | PDE4BL3MBTL1 | |
| SCHEMBL3132672 | 0.79 | PDE4B (0.45) | PDE4BPDE4DPDE4APDE4CL3MBTL1 | |
| SCHEMBL3131168 | 0.78 | SLC6A2 (0.40) | — | |
| SCHEMBL3129548 | 0.78 | L3MBTL1 (0.38) | PDE4BPDE4DPDE4APDE4CL3MBTL1 | |
| SCHEMBL3129484 | 0.74 | F7 (0.43) | — | |
| SCHEMBL30352570 | 0.73 | PDE4B (0.63) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7913450 | 0.73 | PDE4B (0.63) | PDE4BPDE4DPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |