Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.39 |
| ▸ | PDE4A | P27815 | 9/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3126008 | 0.95 | MAPT (0.43) | L3MBTL1ALDH1A1SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL3131168 | 0.94 | SLC6A2 (0.40) | ALDH1A1SMN1; SMN2SLC6A2SLC6A4KDM4E | |
| SCHEMBL3129484 | 0.88 | F7 (0.43) | SLC6A2SLC6A4 | |
| SCHEMBL3118073 | 0.85 | PDE4B (0.44) | L3MBTL1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3120994 | 0.84 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1PDE4BSMN1; SMN2GAA | |
| SCHEMBL3129548 | 0.82 | L3MBTL1 (0.38) | L3MBTL1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3117589 | 0.79 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1PDE4BPDE4APDE4C | |
| SCHEMBL3121033 | 0.76 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1PDE4BPDE4APDE4C | |
| SCHEMBL3123596 | 0.74 | MAPT (0.48) | L3MBTL1ALDH1A1PDE4BSMN1; SMN2KDM4E | |
| SCHEMBL15870719 | 0.73 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |