Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 6/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3207724 | 0.89 | PDE4A (0.36) | PDE4A | |
| SCHEMBL3120994 | 0.89 | L3MBTL1 (0.39) | L3MBTL1PDE4BACHEATMCYP2C9 | |
| SCHEMBL3128372 | 0.82 | L3MBTL1 (0.41) | L3MBTL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3126008 | 0.80 | MAPT (0.43) | L3MBTL1LMNAHPGDTSHRMAPK1 | |
| SCHEMBL3118073 | 0.78 | PDE4B (0.44) | L3MBTL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3120367 | 0.76 | L3MBTL1 (0.39) | L3MBTL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3129210 | 0.76 | PDE4D (0.43) | L3MBTL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3131168 | 0.75 | SLC6A2 (0.40) | LMNAHPGDMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL3131812 | 0.75 | ATM (0.54) | L3MBTL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3129484 | 0.73 | F7 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |