Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844450 | 0.88 | TRPV4 (0.38) | KHKTRPV4CYP11B2ESR1ESR2 | |
| SCHEMBL20597951 | 0.88 | KHK (0.41) | KHKTRPV4CYP11B2ESR1ESR2 | |
| SCHEMBL28314863 | 0.84 | TRPV4 (0.36) | KHKTRPV4CYP11B2ESR1ESR2 | |
| SCHEMBL7922013 | 0.78 | TRPV4 (0.38) | KHKTRPV4CYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL30107963 | 0.78 | TRPV4 (0.38) | KHKTRPV4CYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL27432704 | 0.78 | KEAP1 (0.38) | CYP3A4 | |
| SCHEMBL9488312 | 0.78 | TRPV4 (0.41) | KHKTRPV4CYP11B2ESR1ESR2 | |
| SCHEMBL6081761 | 0.78 | TRPV4 (0.39) | KHKTRPV4ESR1ESR2ALDH1A1 | |
| SCHEMBL10879485 | 0.76 | VCAM1 (0.45) | KHKTRPV4ALDH1A1MAOAMAOB | |
| SCHEMBL8663254 | 0.75 | KHK (0.47) | KHKTRPV4CYP11B2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118894862-A | Indolo [3,2-B ] carbazole structural derivative and electroluminescent device thereof | 西安欧得光电材料有限公司 | 2024-11-05 | — | — | CN | disclosed |