Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 13/20 | 0.44 |
| ▸ | GSK3B | P49841 | 12/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31182010 | 0.79 | BRD4 (0.50) | DYRK1AGSK3BBRD4WNT1RIPK2 | |
| SCHEMBL31182038 | 0.78 | BRD4 (0.43) | DYRK1AGSK3BKCNH2ATMATR | |
| SCHEMBL31181996 | 0.78 | BRD4 (0.45) | DYRK1AGSK3BKCNH2ATMATR | |
| SCHEMBL31182025 | 0.75 | LMNA (0.52) | DYRK1AGSK3BBRD4WNT1LRRK2 | |
| SCHEMBL31182037 | 0.73 | HDAC3 (0.57) | TAS1R3TAS1R1HDAC6 | |
| SCHEMBL31181999 | 0.72 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL31182018 | 0.71 | GSK3B (0.38) | DYRK1AGSK3BKCNH2ATMATR | |
| SCHEMBL31181995 | 0.71 | WNT1 (0.49) | DYRK1AGSK3BBRD4WNT1 | |
| SCHEMBL31182000 | 0.69 | GSK3B (0.45) | DYRK1AGSK3BBRD4WNT1LRRK2 | |
| SCHEMBL31181994 | 0.66 | DYRK1A (0.48) | DYRK1AGSK3BKCNH2WNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878508-A | DC-Rhoin derivative, preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2024-11-01 | — | — | CN | disclosed |