Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | WNT1 | P04628 | 2/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31182025 | 0.84 | LMNA (0.52) | BRD4ACVR1DYRK1AGSK3BWNT1 | |
| SCHEMBL31181996 | 0.83 | BRD4 (0.45) | BRD4PIM1PIM2ACVR1DYRK1A | |
| SCHEMBL31181995 | 0.82 | WNT1 (0.49) | BRD4DYRK1AGSK3BWNT1CCNC | |
| SCHEMBL31182038 | 0.82 | BRD4 (0.43) | BRD4PIM1PIM2ACVR1DYRK1A | |
| SCHEMBL31181982 | 0.79 | DYRK1A (0.44) | BRD4DYRK1AGSK3BWNT1RIPK2 | |
| SCHEMBL31182000 | 0.79 | GSK3B (0.45) | BRD4DYRK1AGSK3BWNT1LRRK2 | |
| SCHEMBL31181994 | 0.77 | DYRK1A (0.48) | DYRK1AGSK3BWNT1 | |
| SCHEMBL22119753 | 0.74 | ACVR1 (0.55) | BRD4PIM1PIM2ACVR1DYRK1A | |
| SCHEMBL23559595 | 0.74 | PIM1 (0.56) | BRD4PIM1PIM2MKNK1MKNK2 | |
| SCHEMBL21818940 | 0.74 | USP30 (0.54) | BRD4PIM1PIM2MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878508-A | DC-Rhoin derivative, preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2024-11-01 | — | — | CN | disclosed |