Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 7/20 | 0.47 |
| ▸ | CDK8 | P49336 | 7/20 | 0.47 |
| ▸ | RET | P07949 | 5/20 | 0.41 |
| ▸ | WNT1 | P04628 | 6/20 | 0.40 |
| ▸ | GSK3B | P49841 | 6/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.39 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31182013 | 0.89 | WNT1 (0.51) | CCNCCDK8RETWNT1GSK3B | |
| SCHEMBL31181992 | 0.87 | WNT1 (0.46) | CCNCCDK8RETWNT1GSK3B | |
| SCHEMBL31181998 | 0.83 | RET (0.47) | RETWNT1GSK3BDYRK1A | |
| SCHEMBL31182018 | 0.75 | GSK3B (0.38) | CCNCCDK8RETWNT1GSK3B | |
| SCHEMBL31182011 | 0.71 | ALDH1A1 (0.53) | — | |
| SCHEMBL31181991 | 0.70 | MEN1 (0.46) | — | |
| SCHEMBL31182025 | 0.67 | LMNA (0.52) | CCNCCDK8WNT1GSK3BDYRK1A | |
| SCHEMBL28513576 | 0.66 | USP30 (0.56) | CCNCCDK8PDK2 | |
| SCHEMBL12108484 | 0.66 | PROKR1 (0.57) | CCNCCDK8 | |
| SCHEMBL20732928 | 0.66 | CCNC (0.53) | CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878508-A | DC-Rhoin derivative, preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2024-11-01 | — | — | CN | disclosed |