Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185026 | 0.86 | KMT2A (0.48) | KMT2ATSHRMAPK1ALDH1A1NPC1 | |
| SCHEMBL31184409 | 0.85 | ALDH1A1 (0.40) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL31184979 | 0.85 | ALDH1A1 (0.46) | KMT2ATSHRMAPK1ALDH1A1NPC1 | |
| SCHEMBL31184657 | 0.83 | ALDH1A1 (0.44) | KMT2ATSHRMAPK1ALDH1A1NPC1 | |
| SCHEMBL31185049 | 0.83 | ALDH1A1 (0.44) | KMT2ATSHRMAPK1ALDH1A1NPC1 | |
| SCHEMBL31184686 | 0.83 | RXFP2 (0.45) | KMT2ATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL31184763 | 0.82 | EPHX2 (0.49) | KMT2ATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL31184520 | 0.82 | KMT2A (0.43) | KMT2ATSHRMAPK1ALDH1A1NPC1 | |
| SCHEMBL31184994 | 0.82 | GRM1 (0.44) | KMT2ATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL31184422 | 0.82 | MAPK1 (0.40) | KMT2ATSHRHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |