Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184723 | 0.95 | NAMPT (0.40) | ALOX5NAMPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL31184929 | 0.93 | ALOX5 (0.40) | ALOX5NAMPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL31184515 | 0.88 | NAMPT (0.42) | ALOX5NAMPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL31184464 | 0.82 | CHKA (0.42) | ALDH1A1POLBCYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184702 | 0.81 | POLB (0.40) | ALDH1A1POLBCYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184570 | 0.81 | ALDH1A1 (0.42) | NAMPTALDH1A1EPHX2POLBCYP1A2 | |
| SCHEMBL31184345 | 0.80 | POLB (0.42) | ALDH1A1POLBCYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184647 | 0.79 | POLB (0.43) | ALDH1A1POLBCYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184933 | 0.79 | POLB (0.41) | ALDH1A1POLBCYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184821 | 0.78 | MAPT (0.42) | ALDH1A1NPSR1RXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |