Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184565 | 0.95 | ALOX5 (0.38) | NAMPTALOX5ALDH1A1NPSR1RXFP1 | |
| SCHEMBL31184515 | 0.93 | NAMPT (0.42) | NAMPTALOX5ALDH1A1NPSR1RXFP1 | |
| SCHEMBL31184929 | 0.88 | ALOX5 (0.40) | NAMPTALOX5ALDH1A1NPSR1RXFP1 | |
| SCHEMBL31184464 | 0.87 | CHKA (0.42) | ALDH1A1POLBCYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184570 | 0.85 | ALDH1A1 (0.42) | NAMPTALDH1A1POLBEPHX2CYP1A2 | |
| SCHEMBL31184345 | 0.85 | POLB (0.42) | ALDH1A1POLBCYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184647 | 0.84 | POLB (0.43) | ALDH1A1POLBCYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184933 | 0.83 | POLB (0.41) | ALDH1A1POLBCYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184500 | 0.83 | POLB (0.38) | ALDH1A1NPSR1POLBCYP1A2CYP3A4 | |
| SCHEMBL31184932 | 0.83 | HPGD (0.38) | ALDH1A1POLBCYP1A2CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |