Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | BRAF | P15056 | 4/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184920 | 0.93 | MALT1 (0.42) | KDRBRAFMALT1SMN1; SMN2TSHR | |
| SCHEMBL31184640 | 0.89 | POLB (0.45) | MALT1SMN1; SMN2TSHRKMT2ALMNA | |
| SCHEMBL31184475 | 0.89 | POLB (0.49) | MALT1KMT2ALMNAMAPK1MEN1 | |
| SCHEMBL31184468 | 0.89 | TP53 (0.44) | MALT1SMN1; SMN2TSHRKMT2ALMNA | |
| SCHEMBL31184711 | 0.88 | MALT1 (0.44) | KDRBRAFMALT1SMN1; SMN2TSHR | |
| SCHEMBL31184972 | 0.88 | POLB (0.44) | MALT1SMN1; SMN2TSHRKMT2ALMNA | |
| SCHEMBL31184902 | 0.87 | MALT1 (0.54) | MALT1SMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL31184818 | 0.86 | ALDH1A1 (0.46) | MALT1SMN1; SMN2TSHRKMT2AMAPK1 | |
| SCHEMBL31184761 | 0.86 | MAPT (0.43) | MALT1SMN1; SMN2TSHRKMT2ALMNA | |
| SCHEMBL31184419 | 0.85 | POLB (0.42) | MALT1SMN1; SMN2TSHRKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |