Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 15/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184499 | 0.93 | MALT1 (0.46) | MALT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31184640 | 0.92 | POLB (0.45) | MALT1SMN1; SMN2ALDH1A1HPGDTSHR | |
| SCHEMBL31184475 | 0.92 | POLB (0.49) | MALT1ALDH1A1HPGD | |
| SCHEMBL31184972 | 0.90 | POLB (0.44) | MALT1SMN1; SMN2ALDH1A1HPGDTSHR | |
| SCHEMBL31184763 | 0.90 | EPHX2 (0.49) | MALT1SMN1; SMN2ALDH1A1HPGDTSHR | |
| SCHEMBL31184468 | 0.89 | TP53 (0.44) | MALT1SMN1; SMN2ALDH1A1HPGDTSHR | |
| SCHEMBL31184818 | 0.89 | ALDH1A1 (0.46) | MALT1SMN1; SMN2ALDH1A1HPGDTSHR | |
| SCHEMBL31184761 | 0.88 | MAPT (0.43) | MALT1SMN1; SMN2ALDH1A1HPGDTSHR | |
| SCHEMBL31184573 | 0.88 | MALT1 (0.46) | MALT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31184994 | 0.88 | GRM1 (0.44) | MALT1SMN1; SMN2ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |