Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184640 | 0.92 | POLB (0.45) | TSHRKMT2AHPGDPOLBMAPK1 | |
| SCHEMBL31184475 | 0.92 | POLB (0.49) | TP53KMT2AHPGDPOLBMAPK1 | |
| SCHEMBL31184972 | 0.90 | POLB (0.44) | TSHRKMT2AHPGDPOLBMAPK1 | |
| SCHEMBL31184902 | 0.89 | MALT1 (0.54) | TSHRHPGDMALT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31184780 | 0.89 | MAPK1 (0.43) | TP53TSHRKMT2APOLBMAPK1 | |
| SCHEMBL31184595 | 0.89 | KDR (0.46) | TSHRKMT2AHPGDPOLBMAPK1 | |
| SCHEMBL31184818 | 0.89 | ALDH1A1 (0.46) | TSHRKMT2AHPGDPOLBMAPK1 | |
| SCHEMBL31184761 | 0.88 | MAPT (0.43) | TSHRKMT2AHPGDPOLBMAPK1 | |
| SCHEMBL31184499 | 0.88 | MALT1 (0.46) | KMT2APOLBMAPK1MALT1TYK2 | |
| SCHEMBL31184820 | 0.88 | MAPK1 (0.49) | TP53TSHRKMT2AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |